Pamela R Westmark Selected Research

Seizures (Absence Seizure)

1/2021	Testing Fmr1 KO Phenotypes in Response to GSK3 Inhibitors: SB216763 versus AFC03127.
1/2020	Preclinical testing of the ketogenic diet in fragile X mice.
11/2018	Rescue of Fmr1KO phenotypes with mGluR5 inhibitors: MRZ-8456 versus AFQ-056.
1/2013	Soy-based diet exacerbates seizures in mouse models of neurological disease.
1/2011	Reversal of fragile X phenotypes by manipulation of AβPP/Aβ levels in Fmr1KO mice.
1/2010	Alzheimer's disease and Down syndrome rodent models exhibit audiogenic seizures.

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Pamela R Westmark Research Topics

Disease

8	Fragile X Syndrome (Martin Bell Syndrome) 01/2022 - 01/2008
7	Alzheimer Disease (Alzheimer's Disease) 01/2021 - 06/2006
6	Seizures (Absence Seizure) 01/2021 - 01/2010
2	Weight Gain 01/2022 - 01/2020
2	Body Weight (Weight, Body) 01/2022 - 01/2020
2	Autistic Disorder (Autism) 01/2020 - 01/2010
2	Down Syndrome (Down's Syndrome) 01/2011 - 01/2010
2	Neuroblastoma 12/2009 - 06/2006
1	Nervous System Diseases (Neurological Disorders) 01/2021
1	COVID-19 01/2020
1	Drug Resistant Epilepsy 01/2020
1	Parkinson Disease (Parkinson's Disease) 11/2018
1	Central Nervous System Diseases (CNS Diseases) 11/2018
1	Thrombosis (Thrombus) 01/2018
1	Hemophilia B (Haemophilia B) 01/2018
1	Ovarian Neoplasms (Ovarian Cancer) 01/2017
1	Ovarian Epithelial Carcinoma 01/2017
1	Pneumonia (Pneumonitis) 02/2008
1	Fibrosis (Cirrhosis) 02/2008
1	Asthma (Bronchial Asthma) 02/2008
1	Airway Remodeling 02/2008

Drug/Important Bio-Agent (IBA)

5	Amyloid beta-PeptidesIBA 11/2020 - 06/2006
5	Proteins (Proteins, Gene)FDA Link 01/2020 - 06/2006
5	Amyloid (Amyloid Fibrils)IBA 01/2013 - 06/2006
3	Metabotropic Glutamate 5 ReceptorIBA 01/2020 - 01/2010
2	Pharmaceutical PreparationsIBA 01/2021 - 11/2018
2	Biomarkers (Surrogate Marker)IBA 01/2021 - 11/2018
2	Amyloid beta-Protein Precursor (Amyloid Protein Precursor)IBA 01/2016 - 01/2010
1	Caseins (Casein)FDA Link 01/2022
1	Phytoestrogens (Phytoestrogen)IBA 01/2022
1	Soybean Proteins (Soy Protein)IBA 01/2022
1	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 01/2021
1	Glycogen Synthase Kinase 3IBA 01/2021
1	Proline (L-Proline)FDA Link 01/2021
1	Glucose (Dextrose)FDA LinkGeneric 01/2020
1	KetonesIBA 01/2020
1	mavoglurantIBA 11/2018
1	Levodopa (L Dopa)FDA LinkGeneric 11/2018
1	MRZ-8456IBA 11/2018
1	Glutamic Acid (Glutamate)FDA Link 11/2018
1	Factor IXa (Coagulation Factor IXa)IBA 01/2018
1	Protein SIBA 01/2018
1	FibrinIBA 01/2018
1	Heparin (Liquaemin)FDA LinkGeneric 01/2018
1	AnticoagulantsIBA 01/2018
1	Proteinase-Activated ReceptorsIBA 01/2017
1	Factor VIIa (Activated Factor VII)IBA 01/2017
1	Thromboplastin (Tissue Factor)IBA 01/2017
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2017
1	Amino Acids FDA Link 01/2011
1	Peptides (Polypeptides)IBA 01/2011
1	Metabotropic Glutamate Receptors (Metabotropic Glutamate Receptor)IBA 01/2011
1	Messenger RNA (mRNA)IBA 12/2009
1	CollagenIBA 02/2008
1	Transforming Growth Factor beta1 (TGF beta 1)IBA 02/2008

Therapy/Procedure

1	Ketogenic Diet 01/2020